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Next-Generation DNA Sequencing Informatics, Second Edition by Stuart M. Brown (2015, Hardcover)
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About this product
Product Identifiers
PublisherCold Spring Harbor Laboratory Press
ISBN-101621821234
ISBN-139781621821236
eBay Product ID (ePID)204343510
Product Key Features
Number of Pages402 Pages
LanguageEnglish
Publication NameNext-Generation D N A Sequencing Informatics, Second Edition
Publication Year2015
SubjectLife Sciences / Molecular Biology, Life Sciences / Cell Biology, Life Sciences / Genetics & Genomics, Genetics
FeaturesRevised
TypeTextbook
Subject AreaScience, Medical
AuthorStuart M. Brown
FormatHardcover
Dimensions
Item Height1.2 in
Item Weight35.3 Oz
Item Length10.3 in
Item Width7.2 in
Additional Product Features
Edition Number2
Intended AudienceScholarly & Professional
LCCN2015-012098
Reviews"Next-Generation DNA Sequencing Informatics (2nd edition)...is a book to get you well and truly started in Bioinformatics....the chapters appear to flow well internally and cover the main aspects of the methods presented. Certainly the QC and RNA-seq chapters will point students or newbioinformaticians in the right direction....this book is likely to be a good one to have on your shelf."--CoreGenomics blog
Dewey Edition23
IllustratedYes
Dewey Decimal572.8/633
Table Of ContentPreface Acknowledgments About the Authors 1. Introduction to DNA Sequencing Stuart M. Brown 2. Quality Control and Data Preprocessing Stuart M. Brown 3. History of Sequencing Informatics Stuart M. Brown 4. Public Sequence Databases Stuart M. Brown 5. Visualization of Next-Generation Sequencing Data Phillip Ross Smith, Kranti Konganti, and Stuart M. Brown 6. DNA Sequence Alignment Efstratios Efstathiadis 7. Genome Assembly Using Generalized de Bruijn Digraphs D. Frank Hsu 8. De Novo Assembly of Bacterial Genomes from Short Sequence Reads Silvia Argimón and Stuart M. Brown 9. De Novo Transcriptome Assembly Lisa Cohen, Steven Shen, and Efstratios Efstathiadis 10. Genome Annotation Steven Shen and Stuart M. Brown 11. Using Next-Generation Sequencing to Detect Sequence Variants Jinhua Wang, Zuojian Tang, and Stuart M. Brown 12. ChIP-seq Stuart M. Brown, Zuojian Tang, Christina Schweikert, and D. Frank Hsu 13. RNA Sequencing with Next-Generation Sequencing Stuart M. Brown and Jeremy Goecks 14. Metagenomics Guillermo I. Perez-Perez, Miroslav Blumenberg, and Alexander V. Alekseyenko 15. Proteogenomics Kelly V. Ruggles and David Fenyö 16. Emerging DNA Sequencing Technologies and Applications Gerald A. Higgins and Brian D. Athey 17. Cloud-Based Next-Generation Sequencing Informatics Konstantinos Krampis, Efstratios Efstathiadis, and Stuart M. Brown Glossary Index
Edition DescriptionRevised edition
SynopsisNext-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making genome and RNA sequencing an affordable and frequently used tool for a wide variety of research applications including variant (mutation) discovery, gene expression, transcription factor analysis, metagenomics, and epigenetics. Bioinformatics methods to support DNA sequencing have become and remain a critical bottleneck for many researchers and organizations wishing to make use of NGS technology. Next- Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies. The remaining chapters from the first edition have been updated with the latest information. This book also provides extensive reference to best- practice bioinformatics methods for NGS applications and tutorials for common workflows. The second edition of Next-Generation DNA Sequencing Bioinformatics addresses the informatics needs of students, laboratory scientists, and computing specialists who wish to take advantage of the explosion of research opportunities offered by new DNA sequencing technologies., ext-Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies., Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making genome and RNA sequencing an affordable and frequently used tool for a wide variety of research applications including variant (mutation) discovery, gene expression, transcription factor analysis, metagenomics, and epigenetics. Bioinformatics methods to support DNA sequencing have become and remain a critical bottleneck for many researchers and organizations wishing to make use of NGS technology. This new edition provides a thorough, plain-language introduction to the necessary informatics methods and tools for analyzing NGS data and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls, and alternative methods. Four new chapters cover experimental design, sample preparation, and quality assessment of NGS data; public databases for DNA sequencing data; de novo transcript assembly; proteogenomics; and emerging sequencing technologies. The remaining chapters from the first edition have been updated with the latest information. This book also provides extensive reference to best-practice bioinformatics methods for NGS applications and tutorials for common workflows. This edition addresses the informatics needs of students, laboratory scientists, and computing specialists who wish to take advantage of the explosion of research opportunities offered by new DNA sequencing technologies. Authors Alexander Alekseyenko Silvia Argimón Brian D. Athey Miroslav Blumenberg Stuart M. Brown Lisa Cohen Efstratios Efstathiadis David Fenyö Jeremy Goecks Gerald A. Higgins D. Frank Hsu Kranti Konganti Konstantinos Krampis Guillermo I. Perez-Perez Kelly V. Ruggles Christina Schweikert Steven Shen Phillip Ross Smith Zuojian Tang Jinhua Wang
LC Classification NumberQP625.N89N485 2015
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