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About this product
Product Identifiers
PublisherSpringer
ISBN-100412830809
ISBN-139780412830808
eBay Product ID (ePID)1780528
Product Key Features
Number of PagesVIII, 246 Pages
LanguageEnglish
Publication NameComparative Genomics
Publication Year2000
SubjectLife Sciences / Biochemistry, Life Sciences / Genetics & Genomics, Genetics, Life Sciences / Zoology / General
TypeTextbook
AuthorMelody Clark
Subject AreaScience, Medical
FormatHardcover
Dimensions
Item Weight21.4 Oz
Item Length9.3 in
Item Width6.1 in
Additional Product Features
Intended AudienceScholarly & Professional
LCCN00-058730
Dewey Edition21
Number of Volumes1 vol.
IllustratedYes
Dewey Decimal572.8/6
Table Of Content1. Comparative genomics: An introduction: sequencing projects and model organisms..- 2. Drosophila melanogaster: A genetic tool.- 3. Tunicates: Models for chordate evolution and development at low genomic complexity..- 4. Fugu rubripes: A fish model genome.- 5. The mouse and the genomic era.- 6. Quantitative Trait Loci in domestic animals -- Complex inheritance patterns..- 7. Comparative genomics of vertebrates and the evolution of sex chromosomes..- 8. Insights into mammalian genome organization evolution by molecular cytogenetics..
SynopsisSince the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis. Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to demonstrate how different approaches taken with model organisms, such as mutation studies, expression profiling of cDNAs, in situ localization of message and comparative genome analysis (both at the gene and nucleotide level) will aid in our understanding of the results coming out of the Human Genome Project and contribute significantly to our understanding of how genes function.