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Handbook of Copper Pharmacology and Toxicology by Edward J Massaro: New
US $242.14
ApproximatelyPHP 13,531.27
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eBay item number:363582805536
Item specifics
- Condition
- Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
- Book Title
- Handbook of Copper Pharmacology and Toxicology
- Publication Date
- 2002-07-01
- Pages
- 608
- ISBN
- 9780896039438
About this product
Product Identifiers
Publisher
Humana Press
ISBN-10
0896039439
ISBN-13
9780896039438
eBay Product ID (ePID)
2258304
Product Key Features
Number of Pages
Xvi, 608 Pages
Publication Name
Handbook of Copper Pharmacology and Toxicology
Language
English
Publication Year
2002
Subject
Biochemistry, Pharmacology
Type
Textbook
Subject Area
Medical
Format
Hardcover
Dimensions
Item Weight
53 Oz
Item Length
10 in
Item Width
7 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2002-067890
Reviews
"...biochemical and molecular researchers from around the globe have produced 35 chapters documenting the present state of knowledge in selected areas of copper pharmacology and toxicology. the state-of-the-art data provided will no doubt stimulate challenging research with this essential trace element required by organism ranging from bacteria to mammals." - Veterinary and Human Toxicology"The book has excellent introductory chapters, and summarizes much recent research at the genetic and cellular levels." - Newsletter of the British Toxicological Society"Dr. Massaro must be congratulated for editing this comprehensive book on copper. There are so many outstanding chapters in this compendium that highlighting any one of them should not detract from the others...this book is a treasure trove of references. The price of the book, though modest for this compendium would be justified for the Preface and the first chapter alone. This book is highly recommended. At the present time it has no equal." -International Journal of Toxicology, "...biochemical and molecular researchers from around the globe have produced 35 chapters documenting the present state of knowledge in selected areas of copper pharmacology and toxicology. the state-of-the-art data provided will no doubt stimulate challenging research with this essential trace element required by organism ranging from bacteria to mammals." - Veterinary and Human Toxicology "The book has excellent introductory chapters, and summarizes much recent research at the genetic and cellular levels." - Newsletter of the British Toxicological Society "Dr. Massaro must be congratulated for editing this comprehensive book on copper. There are so many outstanding chapters in this compendium that highlighting any one of them should not detract from the others...this book is a treasure trove of references. The price of the book, though modest for this compendium would be justified for the Preface and the first chapter alone. This book is highly recommended. At the present time it has no equal." -International Journal of Toxicology
Dewey Edition
21
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
615.9/25652
Table Of Content
I. Copper in Mammals.- 1 Biochemistry and Molecular Biology of Copper in Mammals.- II. Copper Proteins.- 2 Biochemistry of the Wilson's Disease Protein.- 3 Biologically Relevant Properties of Copper-Containing Proteins Analyzed by Means of Semiquantitative and Quantitative Theoretical Descriptors.- 4 Molecular Modeling and Dynamics of Copper Proteins.- 5 The Prion Protein and Copper: What Is the Connection?.- 6 Prion Protein: A Synaptic Cuproprotein.- 7 Cytochrome-c Oxidase.- 8 The Fet3 Protein: A Multicopper Ferroxidase Essential to Iron Metabolism in Yeast.- 9 Interaction of Copper-Binding Proteins from Enterococcus hirae.- III. Copper Transport.- 10 Copper Uptake in Eukaryotic Cells.- 11 The Role of PINA in Copper Transport, Circadian Rhythms, and Wilson's Disease.- 12 The Identification of Motifs Involved in the Intracellular Trafficking of the Menkes Disease Protein.- 13 Intracellular Copper Transport and ATP7B, the Wilson's Disease Protein.- 14 A Multicopper Oxidase-Based Iron-Transport System in Yeast.- IV. Molecular Pathogenesis of Diseases of Copper Metabolism.- 15 Molecular Basis of Diseases of Copper Homeostasis.- 16 Disturbances of Copper Homeostasis and Brain Function.- 17 Role of Copper and Other Transition Metal Ions in the Pathogenesis of Parkinson's Disease, Prion Diseases, Familial Amytrophic Lateral Sclerosis and Alzheimer's Disease.- 18 Molecular Genetics and Clinical Aspects of Menkes Disease and Occipital Horn Syndrome.- 19 The Meaning of Alternative Transcripts of the Menkes Disease Gene.- 20 Expression Profiling in Menkes Disease.- 21 Regulation by Copper of the Expression of Human Bis, a New Gene Involved in the Cellular Stress Response to Metals.- 22 Non-Indian Childhood Cirrhosis: Using a Founder Population to Identify the UnderlyingGenetic Defect.- V. Copper Toxicity and Therapeutics.- 23 Biological Effects of Chronic Copper Exposure.- 24 Copper Toxicity to Tight Junctions in the Human Intestina Caco-2 Cell Line.- 25 Cellular Responses to Copper in Aquatic Organisms: Importance of Oxidative Stress and Alteration of Signal Transduction.- 26 Selective Removal of Copper Accumulating in the Form Bound to Metallothionein by Tetrathiomolybdate.- 27 Control of Copper in Wilson's Disease and Diseases of Neovascularization, such as Cancer.- 28 Copper-Rich Metallothionein Polymers During the Development of Fulminant Hepatitis in LEC Rats: Effect of D-Penicillamine.- VI. Copper Metabolism and Homeostasis.- 29 Sensory Protein Modification: A New Feature in Copper Balancing.- 30 Comparative Analysis of Copper and Iron Metabolism in Photosynthetic Eukaryotes vs Yeast and Mammals.- 31 Copper and the Morphological Development of Streptomyces.- 32 Molecular Hardware of Copper Homeostasis in Enterococcus hirae.- 33 Copper Homeostasis in Plants.- 34 The Role of Copper Ions in Regulating Methane Monooxygenases in Methanotrophs.- 35 Regulatory Responses to Copper Ions in Fungi.
Synopsis
Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in a variety of metabolic diseases, Menkes and Wilson's diseases and occipital horn syndrome, as well as the role of copper in Parkinson's disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer's disease., There is great interest in the pharmacology and toxicology of copper from practitioners across a broad spectrum of biomedical research and clinical disciplines. This book contains studies in prokaryotic organisms and yeast that have identified membrane-associated proteins that mediate the uptake or export of copper from cells. Also vcovered is the identification of proteins of similar function in mammal's revealing a remarkable structural and functional conservation of copper metabolism between bacteria, yeast and humans. Furthermore, studies of the function and localization of the products of the Menkes and Wilson's disease genes have provided valuable insight into the mechanisms of copper balance and their role in maintaining apprpriate copper distribution in mammals. The volume shows results of studies implicating a role of copper in the pathogenesis of neuronal injury in Alzheimer's disease and other prion-associated encephalopathies. The Handbook of Copper Pharmacology and Toxicology, reviews the current status of knowledge pertaining to the research areas noted above, and will be an invaluable reference to researchers and students interested in the copper pharmacology and toxicology in a broad sense.
LC Classification Number
RM300-666
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- 3***t (765)- Feedback left by buyer.Past monthVerified purchaseShipped fast,like new
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Seller feedback (503,840)
- 3***t (765)- Feedback left by buyer.Past monthVerified purchaseShipped fast,like new
- r***r (863)- Feedback left by buyer.Past monthVerified purchaseSolid transaction. No issues to speak of.
- e***e (5489)- Feedback left by buyer.Past monthVerified purchaseBetter than described! Fast shipping, and Immaculate packaging! Thank you! Fantastic seller!