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Toxicology of Glutathione Transferases - 9780849329838

BOOKS etc.
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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
Book Title
Toxicology of Glutathione Transferases
ISBN
9780849329838
Publication Year
2006
Type
Textbook
Format
Hardcover
Language
English
Publication Name
Toxicology of Glutathione Transferases
Item Height
234 mm
Author
Yogesh C. Awasthi
Publisher
Taylor & Francis INC International Concepts
Subject
Chemistry, Biology
Item Weight
726 g
Item Width
156 mm
Number of Pages
375 Pages

About this product

Product Information

Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance. Toxicology of Glutathione Transferases is the only text that details the methods used in GST research. With chapters written by experts who have been involved in all areas of GST research and have actively contributed to the progress of this field, the book describes the role of GSTs in toxicology, focusing on their pharmacologic and physiologic roles and their relevance to biological toxicology. The book provides current information on gene families, structure and regulation of gene expression, reaction mechanisms and substrates, three-dimensional structures of GSTs, design of proteins with GST activity, and various approaches to developing inhibitors that overcome drug resistance. It also covers the physiological significance and the mechanisms of activation of microsomal GSTs. These topics, along with the role of GSTs in detoxification of chemical carcinogens and possible implications of GST polymorphism in human health and disease, make the volume useful to researchers in the field of pharmacology and toxicology. Chapters cover the possible and exciting role of GSTs in defense mechanisms against chronic oxidative stress-linked disorders such as atherosclerosis and the newly emerging area of GST-mediated modulation of stress-signaling through its catalytic as well as binding activities. They explore an intriguing hypothesis that strongly suggests an important role of the factors that modulate the GSH-electrophile conjugate (GS-E) homeostasis in the regulation of cellular processes. Chapters on known and potential endogenous electrophilic substrates and a major role of GSTs in suppressing stress-induced lipid peroxidation reinforce this newly emerging role of GSTs. These are just a few of the features that make the book helpful to clinicians involved in basic as well as tr

Product Identifiers

Publisher
Taylor & Francis INC International Concepts
ISBN-13
9780849329838
eBay Product ID (ePID)
88915107

Product Key Features

Number of Pages
375 Pages
Language
English
Publication Name
Toxicology of Glutathione Transferases
Publication Year
2006
Subject
Chemistry, Biology
Type
Textbook
Author
Yogesh C. Awasthi
Format
Hardcover

Dimensions

Item Height
234 mm
Item Weight
726 g
Item Width
156 mm

Additional Product Features

Editor
Yogesh C. Awasthi
Country/Region of Manufacture
United States

Item description from the seller

Business seller information

Value Added Tax Number:
  • GB 976952259
BOOKS etc.

BOOKS etc.

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BOOKS etc is an UK online business that is based in ALDERSHOT, Hampshire. We are a family run company that aims to bring customers a fantastic selection of books with great prices, with friendly ...
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