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Fibrosis Research: Methods and Protocols

by | HC | VeryGood
US $16.08
ApproximatelyPHP 894.73
Condition:
Very Good
May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend ... Read moreabout condition
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eBay item number:196060952476
Last updated on Aug 24, 2024 04:33:14 PHTView all revisionsView all revisions

Item specifics

Condition
Very Good
A book that has been read but is in excellent condition. No obvious damage to the cover, with the dust jacket included for hard covers. No missing or damaged pages, no creases or tears, and no underlining/highlighting of text or writing in the margins. May be very minimal identifying marks on the inside cover. Very minimal wear and tear. See all condition definitionsopens in a new window or tab
Seller Notes
“May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend ...
Binding
Hardcover
Weight
1 lbs
Product Group
Book
IsTextBook
No
ISBN
9781588294791
Subject Area
Medical
Publication Name
Fibrosis Research : Methods and Protocols
Publisher
Humana Press
Item Length
9.3 in
Subject
Pulmonary & Thoracic Medicine, Diseases
Publication Year
2005
Series
Methods in Molecular Medicine Ser.
Type
Textbook
Format
Hardcover
Language
English
Author
David A. Brenner
Item Weight
30.2 Oz
Item Width
6.1 in
Number of Pages
Xvi, 392 Pages

About this product

Product Identifiers

Publisher
Humana Press
ISBN-10
158829479X
ISBN-13
9781588294791
eBay Product ID (ePID)
8038619046

Product Key Features

Number of Pages
Xvi, 392 Pages
Language
English
Publication Name
Fibrosis Research : Methods and Protocols
Subject
Pulmonary & Thoracic Medicine, Diseases
Publication Year
2005
Type
Textbook
Subject Area
Medical
Author
David A. Brenner
Series
Methods in Molecular Medicine Ser.
Format
Hardcover

Dimensions

Item Weight
30.2 Oz
Item Length
9.3 in
Item Width
6.1 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2005-006567
Reviews
"...a must for the shelf of every researcher and physician interested in fibrotic diseases." -Rheumatology
Dewey Edition
22
Series Volume Number
117
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
616.7/42
Table Of Content
The Clinical Scope of Fibrosis.- Pulmonary Fibrosis.- Renal Fibrosis.- Transforming Growth Factor-?.- Regulation of Extracellular Matrix Metabolism: Cultured Cells.- Isolation and Culture of Skin Fibroblasts.- Isolation and Culture of Hepatic Stellate Cells.- Isolation and Phenotypic Characterization of Lung Fibroblasts.- Methods for Measuring Type I Collagen Synthesis In Vitro.- Methods for Assessing the Molecular Mechanisms Controlling Gene Regulation.- Methods for Measuring TGF-? Using Antibodies, Cells, and Mice.- Studying Fibrosis Using Animal Models.- Morphological Methods for Assessment of Fibrosis.- Methods for Measuring Hydroxyproline and Estimating In Vivo Rates of Collagen Synthesis and Degradation.- Approaches to Evaluation of Fibrogenic Pathways in Surgical Lung Biopsy Specimens.- Animal Models for Adult Dermal Wound Healing.- Modeling Liver Fibrosis in Rodents.- Animal Models of Pulmonary Fibrosis.- Animal Models of Renal Fibrosis.- Animal Models of Cardiac Fibrosis.- Genetic Approaches to Studying Fibrosis.- Finding Fibrosis Genes.- Genetic Studies to Identify Hepatic Fibrosis Genes and SNPs in Human Populations.- Analysis of Microarray Experiments for Pulmonary Fibrosis.- DNA Microarrays and Data Mining To Study Hepatic Fibrosis.- Analysis of Proteins Dominantly Expressed in Hepatic Stellate Cells of Activated Phenotype.
Synopsis
Leading investigators review the highlights of current fibrosis research and the experimental methodologies used uncover the mechanisms that drive it. In their discussion of research methodologies utilizing cultured cells to model various aspects of the fibrotic response in vitro, the authors describe the isolation, characterization, and propagation of mesenchymal cells, and highlight the similarities and differences between methods that are appropriate for different types of fibroblasts. Approaches for studying collagen gene regulation and TGF-b production are also discussed, along with experimental methodologies utilizing animal models to study the pathogenesis of fibrosis. The protocols follow the successful Methods in Molecular Medicine(TM) series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls., Leading investigators review the highlights of current fibrosis research and the experimental methodologies used uncover the mechanisms that drive it. In their discussion of research methodologies utilizing cultured cells to model various aspects of the fibrotic response in vitro, the authors describe the isolation, characterization, and propagation of mesenchymal cells, and highlight the similarities and differences between methods that are appropriate for different types of fibroblasts. Approaches for studying collagen gene regulation and TGF-b production are also discussed, along with experimental methodologies utilizing animal models to study the pathogenesis of fibrosis. The protocols follow the successful Methods in Molecular Medicine(tm) series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
LC Classification Number
RC705-779

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